Efficiency may make a difference nowadays.
I am not sure about a single level but on a 2000sq ft older 2-story home with split systems, the downstairs unit I had from 1992 was 2.5 Tons and 10 SEER rating. It died a horrible death (air handler valve quit, and with R-22 not worth fixing due to cost of replacing the refrigerant and other failed components) and I replaced the units inside and out myself with help from 2 friends.
I replaced it with a 15 seer 2.5 ton. It blows MUCH colder air now set at the same thermostat setting and the house cools down quicker thanks to the variable speed air handler.
The upstairs 1.5 ton SEER 10 unit is still on it's last legs but with us looking to GTHO of this home soon, I'm not putting any more money into anything than I have to.
Just to sum up: Downstairs unit is 2.5 Ton, brick outside walls and crappy 1992 level insulation. 10 foot ceilings. Approximately sq ft cooled is around 1,300sq ft
Upstairs unit is 1.5 Ton, ancient with dirty coils and wood exterior walls, vaulted ceilings in the master, all the heat from downstairs rises into my return. Approx sq ft cooled is 800.
Anyhow, we stay comfortable with the T-stat set over 74 deg